(S)-3-(Toluene-4-sulfonyloxy)-pyrrolidine-1-carboxylic acid tert-butyl ester is an organic compound with the following properties and uses:
Nature:
-Appearance: White crystalline solid
-molecular formula: C17H25NO5S
-Molecular weight: 359.45g/mol
-Melting point: about 56-58 ° C
-Boiling point: About 437.4 ° C
-Density: 1.276g/cm3
-Solubility: Soluble in common organic solvents (such as methanol, chloroform, dimethyl sulfoxide)
Use:
(S)-3-(Toluene-4-sulfonyloxy)-pyrrolidine-1-carboxylic acid tert-butyl ester is commonly used in stereoselective chemical reactions in organic synthesis. It can be used as a synthetic intermediate of chiral compounds and is widely used in the field of medicine, such as drug synthesis and drug research.
Method:
The preparation of (S)-3-(Toluene-4-sulfonyloxy)-pyrrolidine-1-carboxylic acid tert-butyl ester is generally achieved by chemical reaction. Specifically, it can be prepared by esterification of (S)-3-(toluene-4-sulfonyloxy)-pyrrolidine-1-carboxylic acid with tert-butanol.
Safety Information:
(S)-3-(Toluene-4-sulfonyloxy)-pyrrolidine-1-carboxylic acid tert-butyl ester has limited safety information, in general, it should be considered a hazardous chemical. When handling the compound, it is necessary to follow appropriate laboratory safety practices, including wearing appropriate personal protective equipment (such as gloves, protective glasses) and handling in a well-ventilated environment. In the process of storage and handling, it should be stored separately from dangerous chemicals such as oxidants, strong oxidants and strong acids, and kept away from fire and high temperature. Specific recommendations for safe handling require reference to the safety data sheet of the compound and the laboratory's safe handling practices.